Search on: TISSUE INHIBITOR OF METALLOPROTEINASE-1 
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Descriptor English:   Tissue Inhibitor of Metalloproteinase-1 
Descriptor Spanish:   Inhibidor Tisular de Metaloproteinasa-1 
Descriptor Portuguese:   Inibidor Tissular de Metaloproteinase-1 
Synonyms English:   TIMP-1  
Tree Number:   D12.776.926.450
Definition English:   A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a N-glycosylated protein, molecular weight 28 kD, produced by a vast range of cell types and found in a variety of tissues and body fluids. It has been shown to suppress metastasis and inhibit tumor invasion in vitro. 
History Note English:   98; see TISSUE-INHIBITOR OF METALLOPROTEINASE-1 (NM) 1980-97 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   33426 
Unique Identifier:   D019715 

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